News - vermicon AG

News - vermicon AG

vermicon AG



News - vermicon AG

Newsgrafik #34204

Flow VIT®: The Automated Analysis Method for Microbiological Quality Control  (Company news)

Powerful detection system combining VIT® gene probe technology and flow cytometry

As part of the BrauBeviale 2018, vermicon AG presents the powerful Flow VIT® Solution, a combination of flow cytometry and VIT® gene probe technology. This new detection system by vermicon AG, which was developed in cooperation with Sysmex Corporation, aims to raise the microbiological quality control to a higher level and to enable a faster and more cost-efficient monitoring of production processes and end products.

The Flow VIT® Alicyclobacillus test kit is the first application for the fully automated VIT® analysis of microorganisms via flow cytometry. The test kit allows producers in the beverage industry to detect microbial causes of offflavors quickly and reliably. Thus, the quality of beverage products is increased and economically damaging recall actions can be prevented. Samples are prepared with the Flow VIT® test kit. The actual evaluation is fully automated and takes only a few minutes thanks to the flow cytometer CyFlow Cube 6*. Additional innovative applications for the beverage industry are currently being developed.

“We want to provide our customers with a fast and comprehensive view into their microbiological samples. This is the only way to guarantee the highest level of microbiological safety”, remarks Dr. Jiri Snaidr, founder and CEO of vermicon AG. “The Flow VIT® Solution is another milestone on our way to profoundly changing industrial microbiology.”

Another innovation by vermicon AG ist the VIT® Beer Screening test kit. This test kit allows an unambiguous identification of individual beer-spoiling lactic acid bacteria in beer and mixed beer beverages. Up to 16 species of bacteria can be specifically identified in a single sample. In contrast to other rapid detection methods, only living cells are detected with VIT® gene probe technology, i.e. dead cells do not cause false-positive results. Finished products as well as samples from all stages of the brewing process, including yeast propagation, can be examined.

BrauBeviale, the capital goods exhibition for the beverage industry, will be held from 13 to 15 November, 2018 in Nuremberg, Germany. vermicon AG will be presenting its innovative solutions for industrial microbiology in Hall 4, Booth 305.
(vermicon AG)

Newsgrafik #33328

Scan VIT® - The revolutionary microbiological system for a specific, quantitative and automated ...  (Company news)

...single cell detection

Up to now, microbiology meant being dependent on cultivation. Even a lot of modern methods require a pre-enrichment step. The speed propagated for modern methods, however, is almost always achieved at the expense of specificity. In addition, the detection limit is usually significantly above 1.000 cells per mL.

Scan VIT® is revolutionizing microorganism detection:
-Firstly – detection takes a maximum of 4 hours (sampling to result).
-Secondly - detection is highly specific.
-Thirdly - detection is independent from cultivation, individual cells are analyzed directly.
-And fourthly – its sensitivity is 1 cell per sample volume, which can usually amount to up to 100 mL or, depending on the sample material, even larger volumes.

All of the experience gathered over 20 years of our company’s activity in industrial microbiology went into the long years of development work for this disruptive technology.

Specific and quantitative detection of single cells
With a detection limit of 1 cell per sample volume, the new Scan VIT® technology is the long-awaited, necessary revolution in microbiology! Whenever liquid samples have to be tested for microorganisms, a statement about the presence, number and kind of microorganisms in the entire sample volume can be made within a maximum of 3-4 hours. For with the new Scan VIT®, single cells in up to 100 mL sample volume can be detected without cultivation, quantitatively and with high specificity. Hence, the new Scan VIT® can be applied in the beverage sector as well as with drinking or process water – basically, wherever microorganisms have to be detected in liquid matrices. Whether in end product control, control of raw materials or in process control – applying Scan VIT® quickly provides maximum safety.

The advantages
-Detection of single cells
-No cultivation/pre-enrichment required
-Highly specific: cells are identified
-Extremely high sensitivity: 1 cell per sample volume
-Up to 100 ml sample volume can be analyzed
-Also applicable for sample volumes > 100 ml
-Absolute quantification: every single cell is detected
-Completely automated scan of the entire volume within a maximum of 2 hours
-Intelligent signal and cell recognition due to artificial intelligence
-High-performance VIT® Vision Software for scan control and evaluation

Technological development
The new Scan VIT® system consists of three fundamental technological components:
1. VIT® gene probe technology: reliable, tried and tested, scientifically valid and highly specific
2. The Scan VIT® scanner: extremely fast, automated scanning of the sample volume
3. VIT® Vision: artificial intelligence for automated evaluation of completed scans

The incentive for this disruptive innovation was our ambition to be able to provide our customers with a technology that is able to reliably detect a single living cell in a large sample volume specifically and quantify it absolutely. As a result, contaminations can be detected even faster and with higher accuracy.

How does Scan VIT® work?
The Scan VIT® technology is used for analysis and absolute quantification of microorganisms in liquid samples. In contrast to conventional methods, the new Scan VIT® method is characterized by an extremely high sensitivity, with a detection limit of only 1 cell per sample / filtration volume. Consequently, pre-enrichment of the sample is no longer required.

The analysis workflow is simple and short. A defined liquid volume is filtrated and hybridized with the specifically programmed VIT® gene probes. The gene probes bind with high specificity to the individual microorganisms. The filter is scanned sequentially and automatically with the Scan VIT® scanner. Scan control and evaluation of received signals is performed by the VIT® Vision software. With the aid of artificial intelligence, microorganisms are identified specifically and quantified reliably.

Max. 4 hours pass between sampling and results. The evaluation time for positive samples is even shorter.

Artificial intelligence
The VIT® Vision software is the centerpiece of the new, patented Scan VIT® technology. In order to make the ultra-fast, highly specific analysis and evaluation possible, we have programmed a completely new software with a powerful learning algorithm. Due to its integrated artificial intelligence, VIT® Vision recognizes labelled cells specifically and is able to differentiate them from the background. In order to perfect the software’s ability for highly specific cell recognition, several years and around one million learning scans have been invested in the development of the algorithm.

VIT® Vision’s learning algorithm is based on the principles of artificial intelligence. The system learns autonomously how best to recognize a cell specifically!

The Scan VIT® products
The first product able to use the entire power of the new Scan VIT® technology is Scan VIT® E.coli/Coliforms. It allows to test samples for the presence of Escherichia coli and coliform bacteria in a very short time.

In sample volumes of up to 100 mL or more, even a single cell is detected. Identification and quantification of the entire sample is fully completed after max. 4 hours.

New products are already being developed. In the next weeks and months, new products for application with the new Scan VIT® technology will continuously be made available to our customers.
(vermicon AG)

Last database update: 02.06.2020 16:40 © 2004-2020, Birkner GmbH & Co. KG